Expression of VEGF in Fallopian tubes in Ovarian Ischemia-Reperfusion

Aim: Our aim was to investigate expression level of VEGF in tuba uterine ovarian ischemia-reperfusion (I/R) by immunohistochemical techniques. Material and Methods: 30 Sprague Dawley female rats were categorized into three groups. Sham group: The abdomen opened closed without any treatment. Ischemia (I) 1-hour ischemia allowed create ischemic injury. Ischemia-reperfusion then 3-hour reperfusion I/R Results: MDA MPO levels increased after IR while GSH content decreased. Histological scores follicular degeneration, inflammation, hemorrhage high I Normal histology observed sham group. In group, degenerated cilia, desquamative epithelial cells impaired basement membrane leukocytes infiltration, apoptotic nuclei, vascular dilatation, thrombosis inflammation adenoma observed. mainly endothelial cells, structures, vessels, macrophage inflammatory leukocyte fibroblast showed positive expression. Conclusion: damage affected angiogenesis, changes implantation.